15 facts about spinal muscular atrophy in Maine Coon cats
Here are 15 facts about spinal muscular atrophy (SMA) in Maine Coon cats. SMA in a young non-Maine Coon. Image believed to be in the public domain and from a study: "Failure of lower motor neuron radial outgrowth precedes retrograde degeneration in a feline model of spinal muscular atrophy." SMA is an inherited genetic disease in Maine Coon cats causing a decreased muscle mass. If two carrier cats, that is cats which are heterozygous to the disease which means they carry one copy of the gene mutation, are mated there is a 25% probability of the offspring being affected. This means that 25% of the offspring will be homozygous to the disease which in turn means that they have two copies of the gene mutation. The disease will be present in them. The disease affects the spinal cord nerves that control the skeletal muscles of the body and legs. The spinal cord nerves die off. The disease is evident at about 3 to 4 months of age. Kittens move with a sway in the rear end. By the ag...