Aficamten for the treatment of HCM in the Maine Coon and other cats
Aficamten for the treatment of HCM in the Maine Coon and other cats. Image: MikeB A study - referred to at the end of the article - concludes with the words below in testing a new drug called aficamten for the treatment of hypertrophic cardiomyopathy (HCM) in cats of which the Maine Coon is perhaps the best known cat breed to suffer from this inherited disease. "A single dose of aficamten significantly decreased LV systolic function and improved LVOTO, both of which are harmful aspects of this disease process that contribute to the pathogenesis." The sentence above describes the effects of this medication called aficamten on a condition that causes abnormal function in the left ventricle of the heart which is how HCM is manifested in cats and people. The left ventricle becomes enlarged and malfunctions. Here's a breakdown: A single dose of aficamten significantly decreased LV systolic function: Aficamten reduces the pumping ability of the left ventricle (LV) to a noticea...